http://www.health-andme.com/testosterone-booster/
This ingredient is extract of Urtica Diodica, or more commonly known also as the nettle. Now before you start, if you decide to buy a product with this ingredient be sure to get the standard for that ingredient, not just "nettle extract" or "Diodica Urtica extract. With these you do not know how their sample is concentrated for this ingredient.
How many 3.4-Divanillytetrahydrofuran work?
3.4-Divanillyltetrahydrofuran works primarily by binding to sex hormone-binding globulin (SHBG). How do SHBG binds to sex hormones, especially testosterone and estradiol. So the function Basic SHBG is to regulate the amount of biologically active hormones in your body. The reasons for this are unclear, but I guess because your body likes balance. Anyway, now that we know what is SHBG that we can understand how the 3.4-Divanillytetrahydrofuran works. It attaches to SHBG, rendering it inactive so it is then unable to bind to sex hormones. This will, in theory, your testosterone and free estradiol to rise, and we know that high testosterone promotes muscle growth.
And now for research.
There are only few newspapers have written on this principle because, unfortunately none is free, but they noted 3.4-binding Divanillyltetrahydrofuran affinity for SHBG. In a newspaper, they state "All except the lignans (-)-pinoresinol developed a binding affinity to SHBG in vitro test. The affinity of (-) -3,4-Divanillyltetrahydrofuran was exceptionally high (1). Another newspaper said the same thing, "Lignans bind to sex hormone-binding globulin (SHBG). The lignan with greater binding affinity is (+/-)- 3,4-divanillyltetrahydrofuran "(2). Although we are not able to see the research as known fact that information from the abstract does not specify that the 3.4-divanillyltetrahydrofuran attached to SHBG. This shows that the claim is true, however, how action is not known. Many people ran sponsored / unsponsored logs from this material and also had blood tests done showing free testosterone before and after, so if you want to see some anecdotal comments, which you can find online.
Can it help bodybuilders other means?
Nettles also has other functions that might be useful to bodybuilders. A newspaper revealed that the nettle has glucose lowering capacity, or is antihyperglycemic (3). In addition, a newspaper said that the glucose lowering abilities were to cause increased secretion of insulin in the Islets Langerhance (these are the cells that produce hormones in the pancreas) (4). This research suggests that nettle may be used to manipulate insulin as well. However, they do not say what type of extract or part of the plant they used, so I would avoid buying nettle for handling of insulin.
References:
1. Schottner, M., Gansser G., and D. Spiteller. "Lignans from the roots of Urtica dioica and their metabolites bind to sex hormone binding globulin Rights (SHBG). "Planta Med. 63 (1997): 529-32. PubMed." Http: / / www.ncbi.nlm.nih.gov/pubmed/9434605ordinalpos=1&itool=EntrezSystem2.PEntrez.
Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA & linkpos = 2 & log $ =
relatedarticles = pubmed & logdbfrom>.
2. Schöttner, M. D. Gansser, and G. Spiteller. "Interaction of lignans with sex hormones of the human binding globulin (SHBG)." Z Naturforsch C. 52 (1997): 834-43. PubMed. "Http: / / www.ncbi.nlm.nih.gov/pubmed/9463941?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.
Pubmed_DefaultReportPanel.Pubmed_RVDocSum>.
3. Bnouham Mohamed, Mohammed Aziz, Abdelkhaleq Legssyer, et al. "Activity Antihyperglycemic extract aqueous Urtica dioica. "Fitoterapia 74 (2003): 677-81. Science Direct. <h title = "active links once published"> ttp: / / target = "_blank"> www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VSC-4B12XJ5-8&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=935290942&_
rerunOrigin = scholar.google & _acct = C000050221 & _version = 1 & _urlVersion _userid = 0 & = 10 & md5 = f6c71b0dcb4
d6265abd914cded5ec522>.
4.Farzami, B. D. Ahmadvand, Sh Khaghani, et al. "Induction of insulin secretion by a component of Urtica dioica leave extract in islets perifused Langerhans and its effects in vivo in normal and streptozotocin diabetic rats. "J Ethnopharmacol 89 (2003): 47-53. PubMed. <Title = "active links once published"> http://www.ncbi.nlm.nih.gov/pubmed/14522431?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_
Discovery_RA & linkpos = 4 & log $ relatedarticles = pubmed & logdbfrom =>.
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Article Source: ArticlesBase.com – 3,4-Divanillyltetrahydrofuran; A Potent Testosterone Booster
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